The number of included clinical studies was limited to 20 with a heterogeneous mix of study designs.

Consensus Statement 1: A mean 3-D deviation is reported for static computer-aided implant surgery at various points of measurement

The mean 3-D deviation for static computer-aided implant surgery (s-CAIS) at the entry point was 1.2 mm [1.04, 1.44, 95% CL], at the apical position was 1.5 mm [1.29, 1.62 mm, 95% CL], and for angular deviation was 3.5 [3.00, 3.96, 95% CL]. This Consensus Statement is based on 20 clinical trials (one RCT, 11 UPCSs, and eight URCSs).

Consensus Statement 2: With s-CAIS, there is a vertical discrepancy of −0.25 and −0.57 mm between the planned and actual positions in the apical point of the implant

With s-CAIS, there is a vertical discrepancy in the apical point of the implant between the planned and actual positions of −0.25 and −0.57 mm, 95% CL. This Consensus Statement is based on eight publications (one RCT, five UPCSs, and two URCSs).

Consensus Statement 3: With s-CAIS, there is a vertical discrepancy of −0.08 and 1.13 mm between the planned and actual positions in the apical point of the implant

With s-CAIS, there is a vertical discrepancy in the apical point of the implant between the planned and actual positions of −0.08 and 1.13 mm, 95% CL. This Consensus Statement is based on four publications (three UPCSs and one URCSs).

Consensus Statement 4: Partially edentulous cases show better accuracy using s-CAIS compared to fully edentulous cases

Partially edentulous cases show better accuracy using s-CAIS compared to fully edentulous cases. This Consensus Statement is based on eight publications (one RCT, five UPCSs, and two URCSs).

1) s-CAIS should be considered as an additional tool for diagnosis & treatment planning

Static computer-aided implant surgery (s-CAIS) should be considered as an additional tool for comprehensive diagnosis, treatment planning and surgical procedures.

2) s-CAIS should be prosthetically driven

3) Experience and training are required to achieve favorable outcome when using s-CAIS

Surgical experience and general comprehensive training are desirable to achieve an accurate and favorable outcome for implants placed using s-CAIS.

4) A safety margin of 2mm from critical anatomical structures should be maintained

While recent studies indicate improved accuracy when using s-CAIS in partially edentulous cases, a safety margin of 2mm from critical anatomical structures should be maintained.

5) Alignment of surface scans with 3D volumetric imaging data is recommended to improve the accuracy

The alignment of surface scans, including the prosthetic planning, with 3D volumetric imaging data is recommended to improve the accuracy of the anatomical position of the implant.

6) Surgical guides should be digitally designed on surface scan files aligned with DICOM data

Surgical guides should be digitally designed on surface scan files which have been aligned with DICOM data, which is more accurate than using DICOM data alone.

7) Manufacturer’s guidelines should be followed for optimal accuracy

Manufacturer’s guidelines should be followed with respect to calibration protocols, for all hardware to maintain optimal accuracy.